Children's Fever Medicine Frequently Asked Questions
Find accurate information about Tylenol, Motrin, and other children's fever medicines
⚠️ This FAQ is for general reference only. Always consult your pediatrician or pharmacist before giving medication.
When to Give Medicine
Give fever medicine when temperature is 101.3°F or higher, or 100.4°F or higher if your child is uncomfortable.
Dosing Intervals & Frequency
Give Tylenol (acetaminophen) every 4-6 hours as needed, with a maximum of 5 doses in 24 hours.
Give Motrin/Advil (ibuprofen) every 6-8 hours as needed, with a maximum of 3-4 doses in 24 hours.
Alternating is possible with minimum 2-3 hour gaps, but experts generally recommend using one medicine only to avoid dosing errors.
Product Comparison & Selection
For infants under 6 months, use Tylenol only. For older children, either works; Motrin/Advil has anti-inflammatory effects.
Different concentrations. Infant Motrin is more concentrated (50mg/1.25mL) than Children's Motrin (100mg/5mL). Do not use the same dose.
Safety & Administration
Tylenol (acetaminophen) can be given on an empty stomach, but Motrin/Advil (ibuprofen) must be given with food or milk.
Tylenol maximum 5 doses per day, Motrin/Advil maximum 3-4 doses per day.
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